Resources

HNCIG provides a range of scientific resources to support researchers and clinicians involved in head and neck cancer research.

These include:

International consensus guidelines
Harmonised clinical trial datasets
Methodological frameworks for international studies
Publications from collaborative research projects.

Recent work includes the development of minimum datasets for head and neck cancer clinical trials and research, supporting global data harmonisation.

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HNCIG-EPIC-OPC: Prognostic implications of P16 and HPV discordance: A multinational analysis

Publication

Report published in Lancet Oncology.

HNCIG-epic-opc: prognostic implications of P16 and HPV discordance: a multinational analysis, published in Lancet Oncology

Publication

p16INK4a (p16) immunohistochemistry is the most widely used biomarker assay for inferring HPV causation in oropharyngeal cancer in clinical and trial settings. However, discordance exists between p16 and HPV DNA or RNA status in some patients with oropharyngeal cancer. We aimed to clearly quantify the extent of discordance, and its prognostic implications.

HNCIG consensus guidelines for postoperative radiation in complex cutaneous squamous cell carcinoma

Consensus Documents
Guidelines
Publication

HNCIG published an important guideline for defining postoperative RT volumes post-resection, aiming to promote harmonization of post-operative RT globally and to reduce treatment variation among clinicians.

HNCIG international consensus recommendations for head and neck surgical oncology practice during COVID-19 pandemic

Consensus Documents
Publication

Recommendations for optimizing consistency of practice and reducing uncertainty in care in the setting of pandemic and acute severe resource constraint.

HNCIG framework for future de-escalation studies: De-escalation after DE-ESCALATE and RTOG 1016

Consensus Documents
Guidelines
Publication

The Head and Neck Cancer International Group identified the need to issue guidance regarding future de-escalation studies for patients with HPV-positive head and neck cancer to avoid the possibility of patients being harmed.

Guidelines on CTV-P delineation in laryngeal, hypopharyngeal, and oral cavity squamous cell carcinomas

Guidelines
Publication

These guidelines were published appears in Radiother Oncol. 2018 Jan (DOI: 10.1016/j.radonc.2017.10.016).

Intergroup consensus guidelines on CTV-P delineation in laryngeal, hypopharyngeal, oropharyngeal, and oral cavity squamous cell carcinomas

Consensus Documents
Guidelines
Publication

HNCIG member groups recently published an important guideline

International guideline for the delineation of the Clinical Target Volumes (CTV) for nasopharyngeal carcinoma

Guidelines
Publication

Members of the intergroup published an important guideline for delineation of the clinical target volumes (CTV) for nasopharyngeal carcinoma. The article appears in Radiother Oncol. 2017 Nov 15 (DOI: 10.1016/j.radonc.2017.10.032).